Esomeprazole Sodium

Applications
（1）As a treatment for gastroesophageal reflux disease (GERD) with erosive esophagitis (EE) when oral therapy is not indicated；
（2）For low-risk patients with acute gastric or duodenal ulcer bleeding who are not suitable for oral therapy Forrest classification llc-Ⅲ under gastroscop.
Original research
ASTRAZENECA PHARMS
Original research
ASTRAZENECA PHARMS
Original research

Project Evaluation

Lliterature research
Route screening
Purchasing materials
Cost calculation

The main production equipment

Reactors ( SS,GL,Ti)
capacity up to 8000L;
Reaction conditions：
-90~250℃ 2mmG~60atm
Double Cone/Vacuum Dryer

Professional Reagents

Lithium aluminum hydride, sodium cyanide, lithium tri-sec-butyl borohydride, diisobutyl aluminum hydride
Grignard reagent, borane reagent, lithium reagent

Special process reaction

Chiral resolution, chiral-induced reaction, light reaction, enzyme catalysis, microchannel flow reaction, ozonation reaction, metal-catalyzed coupling reaction, hydrogenation, reaction regardless of anoxic

Riociguanin

Applications

（1）Chronic thromboembolic pulmonary hypertension (CTEPH) with or without surgery;

（2）Pulmonary hypertension(PAH)

Original research

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